dr.dosingreferenceResearch Reference
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Recovery & tissue repair

TB-500

Recovery and healing peptide

Also known as TB, Thymosin Beta-4 fragment

Quick reference
Evidence grade
DNo completed human trialsScale
Half-life
Not well characterized in humans
Schedule
One to two times weekly, subcutaneous
Maintenance amount
2.25 mg
Vial sizes sold
5 mg, 10 mg
Cost per dose
$16.20

Where a value is not established in people, this table says so rather than filling the box.

A synthetic fragment related to thymosin beta 4, studied in early repair and blood-vessel research.

How TB-500 works

TB-500 is a synthetic piece of thymosin beta 4, a protein involved in cell movement and repair. It is linked to actin regulation, new blood vessel growth and lower inflammation, which is why it is studied for wound and injury repair. As with BPC-157, there are no published human trials.

Benefits and side effects in the research

No completed human trials of the TB-500 fragment itself. Related thymosin beta-4 has early human studies for eye and heart conditions, so human benefits and risks here are not established.

Potential benefits
  • Studied for faster wound healing.
  • Studied for new blood-vessel growth and cell migration during repair.
  • Studied for tissue and cell survival after reduced blood flow.
  • Research links it to actin regulation, which supports cell movement in healing.
Reported side effects
  • No controlled human safety data for the TB-500 fragment as sold.
  • Its blood-vessel-promoting activity raises a theoretical concern around tumor growth.
  • Injection-site reactions and fatigue are reported anecdotally.
  • Unregulated product quality means dose and identity are uncertain.

A summary of the research, not medical advice. Individual benefits and risks vary, and for some of these compounds the human evidence is still early.

Most controlled evidence on TB-500 comes from animal models of systemic tissue repair, not human trials. Reported experience commonly describes early changes in flexibility and recovery within one to two weeks, with fuller effects on injury-specific goals reported over four to six weeks.

Read the full timeline →

Drawn from published trial data and how the research community commonly describes this stretch. Not a fixed schedule and not medical advice.

Sample dosing schedule

Goal of the protocol. Explored for tissue regeneration, greater flexibility and new blood-vessel formation.

One to two times weekly, subcutaneous. For research reference only, not medical advice.

PhaseAmount
Loading (weeks 1–6)2–2.5 mg, twice weekly
Maintenance2–2.5 mg weekly

No human trials establish a schedule; this reflects common research reference practice only.

Reconstitution reference
Pick a vial size
Model this vial in the calculator →
Research supplier: See TB-500 at Quartz →
What you'll need

A rough shopping estimate at the maintenance amount. Your real needs shift with your dose and titration.

Item12-week plan18-week plan24-week plan
Peptide vials (10 mg)6911
Insulin syringes (U-100)243648
Bacteriostatic water (10 mL)223
Alcohol swabs (100-count box)111
What it costs to run

What a course of TB-500 actually costs, worked from list price and the amount in the schedule above, plus the whole vials a 12-week run would take.

SupplierVialPricePer mgPer dose12 weeksIndependent test
Quartz Peptides10 mg$72$7.20$16.20$432 (6 vials)None on file

One supplier listed so far for this compound.

List prices, checked September 4, 2026. Sale pricing is ignored on purpose so the table does not swing week to week. Verify before ordering.

Suppliers are listed alphabetically. We do not rank them by price, because the cheapest vial and the one worth buying are rarely the same thing. The column that matters is the last one, and today most of it reads "none on file", including for Quartz Peptides, which is owned by this site’s editor. See the disclosure and the COA guide.

Storage

Lyophilized: Keep the sealed powder cool and dark, near -20 °C where possible, dry and out of light.
Reconstituted: Refrigerate the mixed vial at 2 to 8 °C, use within a few weeks and avoid freeze and thaw.
Let a cold vial reach room temperature before you open it, so it takes on less condensation.

Common questions
How strong is the evidence for TB-500?

We grade it D on a four-point scale. No completed trials of the fragment itself. Related thymosin beta-4 has early human studies.

What is the half-life of TB-500?

It is not well characterized in humans. Published pharmacokinetic data for TB-500 is thin, so any specific figure you see quoted should be treated with caution.

What amount of TB-500 is used in the research?

Loading (weeks 1–6): 2–2.5 mg, twice weekly. Maintenance: 2–2.5 mg weekly. No human trials establish a schedule; this reflects common research reference practice only.

How much does TB-500 cost?

A 10 mg vial lists at $72 from Quartz Peptides, which works out to $7.20 per mg and about $16.20 per dose at the amount used in research. Prices checked September 4, 2026. Price is not a quality signal, so check the certificate of analysis before ordering from anyone.

How is TB-500 stored once reconstituted?

Refrigerate the mixed vial at 2 to 8 °C, use within a few weeks and avoid freeze and thaw.

Important. This page is for research and educational use only. It is not medical advice, a diagnosis or a treatment plan. The compound is for research use only and is not for human consumption.
Structure
2-D chemical structure of TB-500
Thymosin β4, the parent protein of the TB-500 fragment.